Reporter cell lines_ver.2

2022-04-15
조회수 3667

※ InvivoGen 세포 활용 연구

  • 특정 유전자의 기능 연구                                       
  • Cell signaling pathway/signal transduction
  • Cytokine 생산 확인 
  • Antibody 기능 검증
  • PRR Agonist / Antagonist 스크리닝
  • Human cell lines: A549, HCT116, HEK293, HeLa, HepG2, HT29, Jurkat, Ramos, THP-1
  • Mouse cell lines: B16, J774, RAW264.7

※ 두 가지 reporter system 제공

  • SEAP(secreted embryonic alkaline phosphatase)
  • Lucia luciferase
  • InvivoGen의 detection reagent를 이용하여 cell culture supernatant에서 reporter protein을 측정합니다.


※ PRR reporter cells

TLR reporter cells
● : Colorimetric (620-655 nm) /  : Luminescent
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
HEK293 (human)HEK-Blue™ hTLR2Human TLR2 / NF-κB-reporter cellshkb-htlr2
HEK-Blue™ hTLR2-TLR1Human TLR2-TLR1/ NF-κBhkb-htlr21
HEK-Blue™ hTLR2-TLR6Human TLR2-TLR6 / NF-κBhkb-htlr26
HEK-Blue™ hTLR2 KO-TLR1/TLR6Human TLR2 / NF-κB, knockout of human TLR2 and TLR6hkb-htlr2k16
HEK-Blue™ hTLR3Human TLR3 / NF-κBhkb-htlr3
HEK-Blue™ hTLR4Human TLR4-MD2-CD14 / NF-κBhkb-htlr4
HEK-Blue™ hTLR5Human TLR5 / NF-κBhkb-htlr5
HEK-Blue™ hTLR7Human TLR7 / NF-κBhkb-htlr7v2
HEK-Blue™ hTLR8Human TLR8 / NF-κBhkb-htlr8
HEK-Blue™ hTLR9Human TLR9 / NF-κBhkb-htlr9
HEK-Blue™ mTLR2Mouse TLR2 / NF-κBhkb-mtlr2
HEK-Blue™ mTLR3Mouse TLR3 / NF-κBhkb-mtlr3
HEK-Blue™ mTLR4Mouse TLR4-MD2-CD14 / NF-κBhkb-mtlr4
HEK-Blue™ mTLR5Mouse TLR5 / NF-κBhkb-mtlr5
HEK-Blue™ mTLR7Mouse TLR7 / NF-κBhkb-mtlr7
HEK-Blue™ mTLR8Mouse TLR8 / NF-κBhkb-mtlr8
HEK-Blue™ mTLR9Mouse TLR9 / NF-κBhkb-mtlr9
HEK-Blue™ mTLR13Mouse TLR13 / NF-κBhkb-mtlr13
HEK-Dual™ hTLR2Double readout (NF-κB / IL-8), human TLR2, Lucia knocked into IL-8● / hkd-htlr2ni
HEK-Dual™ hTLR3Double readout (NF-κB / IL-8), human TLR3, Lucia knocked into IL-8● / hkd-htlr3ni
HEK-Dual™ hTLR5Double readout (NF-κB / IL-8), human TLR5, Lucia knocked into IL-8● / hkd-htlr5ni
HEK-Dual™ hTLR9Double readout (NF-κB / IL-8), human TLR9, Lucia knocked into IL-8● / hkd-htlr9ni
HEK-Dual™ mTLR4Double readout (NF-κB / IL-8), mouse TLR4-MD2-CD14, Lucia knocked into IL-8● / hkd-mtlr4ni
HEK-Dual™ mTLR7Double readout (NF-κB / IL-8), mouse TLR7, Lucia knocked into IL-8● / hkd-mtlr7ni
THP-1 (human)THP1-Dual™ KO-TLR2NF-κB & IRFs, knockout of human TLR2● / thpd-kotlr2
THP1-Dual™ KO-TLR4 NF-κB & IRFs, knockout of human TLR4 ● / thpd-kotlr4
THP1-Dual™ KO-TLR8NF-κB & IRFs, knockout of human TLR8● / thpd-kotlr8
THP1-Dual™ hTLR9Human TLR9 / NF-κB & IRFs● / thpd-htlr9
RAW (mouse)RAW-Dual™ KO-TLR4Double readout (IRFs / MIP), knocked out for mouse TLR4● / rawd-kotlr4
CLR reporter cells
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
HEK293 (human)HEK-Blue™ hDectin-1aHuman Dectin-1a / NF-Κbhkb-hdect1a
HEK-Blue™ hDectin-1bHuman Dectin-1b / NF-κBhkb-hdect1b
HEK-Blue™ mDectin-1bMouse Dectin-1b / NF-κBhkb-mdect1b
HEK-Blue™ mDectin-2Mouse Dectin-2 / NF-κBhkb-mdect2
HEK-Blue™ mMincleMouse Mincle / NF-κBhkb-mmcl
NOD reporter cells
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
HEK293 (human)HEK-Blue™ hNOD1Human NOD1 / NF-κBhkb-hnod1
HEK-Blue™ hNOD2Human NOD2 / NF-κBhkb-hnod2
HEK-Blue™ mNOD1Mouse NOD1 / NF-κBhkb-mnod1
HEK-Blue™ mNOD2Mouse NOD2 / NF-κBhkb-mnod2
RLR reporter cells
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
A549 (human) A549-Dual™ KO-MDA5NF-κB & IRFs, knockout of human MDA-5● / a549d-komda5
A549-Dual™ KO-RIG-INF-κB & IRFs, knockout of human RIG-I● / a549d-korigi
A549-Dual™ KO-MAVSNF-κB & IRFs, knockout of human MAVS● / a549d-komavs
RAW (mouse) RAW-Lucia™ ISG-KO-MDA5 IRFs, knockout of mouse MDA-5rawl-komda5
RAW-Lucia™ ISG-KO-RIG-I IRFs, knockout of mouse RIG-Irawl-korigi
RAW-Lucia™ ISG-KO-MAVSIRFs, knockout of mouse MAVSrawl-komavs
HEK293 (human)HEK-Lucia™ RIG-IIRFs, overexpression of human RIG-Ihkl-hrigi
THP1 (human)THP1-Dual KO MDA-5NF-κB & IRFs, knockout of human MDA-5● / thpd-komda5
THP1-Dual KO RIG-INF-κB & IRFs, knockout of human RIG-I● / thpd-korigi
THP1-Dual KO MAVSNF-κB & IRFs, knockout of human MAVS● / thpd-komavs
Cytosolic DNA sensor & STING reporter cells
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
B16 (mouse)B16-Blue™ ISG-KO-STINGIRFs, knockout of mouse STINGbb-kostg
HEK293 (human)HEK-Blue™ ISG-KO-STINGIRFs, knockout of human STINGhkb-kostg
293-Dual™ hSTING-A162Double readout (IRFs & IFN-β), Lucia knocked into IFN-β, S162A human STING transfected● / 293d-a162
293-Dual™ hSTING-H232Double readout(IRFs & IFN-β), Lucia knocked into IFN-β, R71-G230-H232-R293 human STING transfected ● / 293d-h232
HEK-Blue STAT6-hSTING R232STAT6-specific SEAP expression hkb-st6r232
293-Dual™ hSTING-R232Double readout (IRFs & IFN-β), Lucia knocked into IFN-β, R71-G230-R232-R293 human STING transfected● / 293d-r232
293-Dual™ mSTINGDouble readout (IRFs & IFN-β), Lucia knocked into IFN-β, mouse STING transfected● / 293d-mstg
RAW (mouse) RAW-Lucia™ ISG-KO-cGASIRFs, knockout of mouse cGASrawl-kocgas
RAW-Lucia™ ISG-KO-IFI16IRFs, knockout of mouse IFI16 Lucia rawl-koif16rawl-koif16
RAW-Lucia™ ISG-KO-STINGIRFs, knockout of mouse STINGrawl-kostg
Raw-lucia ISG-KO-TREX1IRFs, knockout of mouse TREX1rawl-kotrex
THP-1 (human)THP1-Dual™ KO-cGASNF-κB & IRFs, knockout of human cGAS● / thpd-kocgas
THP1-Dual™ KO-IFI16NF-κB & IRFs, knockout of human IFI16● / thpd-koifi16
THP1-Dual™ KO-STINGNF-κB & IRFs, knockout of human STING● / thpd-kostg
THP1-Dual™ KI-hSTING-A162NF-κB & IRFs, knockin of S162A human STING (DMXAA sensitive isoform)● / thpd-a162
THP1-Dual™ KI-hSTING-H232NF-κB & IRFs, knockin of R71-G230-H232-R293 human STING● / thpd-h232
THP1-Dual™ KI-hSTING-M155NF-κB & IRFs, knockin of V155M human STING (constitutively active isoform)● / thpd-m155
THP1-Dual™ KI-hSTING-R232NF-κB & IRFs, knockin of R71-G230-R232-R293 “wild-type” human STING● / thpd-r232
THP1-Dual™ KI-hSTING-S154NF-κB & IRFs, knockin of N154S human STING (constitutively active isoform)● / thpd-s154
THP1-Dual™ KI-mSTINGNF-κB & IRFs, knockin of mouse STING● / thpd-mstg
THP1-Dual™ KO-TREX1NF-κB & IRFs, knockin of human TREX1● / thpd-kotrex
ALPK1/TIFA
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
HEK293 (human)HEK-Blue™ KO-ALPK1Knockout (KO) of the ALPK1 genehkb-koalpk
HEK-Blue™ KO-TIFAKnockout (KO) of the TIFA genehkb-kotifa


※ TRANSCRIPTION FACTOR reporter cells

Transcription factor reporter cells (Human)
● : Colorimetric (620-655 nm) /  : Luminescent
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
A549 (human) A549-Dual™NF-κB & IRFs● / a549d-nfis
HCT116 (human)HCT116-Dual™NF-κB & IRFs● / hctd-nfis
HEK293 (human)HEK-Blue™ ISGIRFshkb-isg
293-Dual™ NullDouble readout (IRFs/ IFN-β), Lucia knocked into IFN-β● / 293d-null
HEK-Dual™ NullDouble readout (NF-κB / IL-8), Lucia knocked into IL-8● / hkd-nullni
HepG2 (human)HepG2-Dual™NF-κB & IRFs● / hepg2d-nfis
HepG2-Lucia™ AhRAhRhpgl-ahr
HT29 (human)HT29-Lucia™AhRht2l-ahr
Jurkat (human)Jurkat-Dual™NF-κB & IRFs● / jktd-isnf
Jurkat-Lucia™ NFATNFATjktl-nfat
Jurkat-Lucia™ NFAT-CD16NFAT, human CD16A (FcγRIIIA, V158 allotype) transfectedjktl-nfat-cd16
Ramos (human)Ramos-Blue™NF-κB / AP-1 rms-sp
Ramos-Blue™ KD-MyDNF-κB / AP-1, knockdown of human MyD88 rms-kdmyd
THP-1 (human)THP1-Blue™NF-κB NF-κBthp-nfkb
THP1-Lucia™ NF-κBNF-κBthpl-nfkb
THP1-Blue™-ISGIRFsthp-isg
THP1-Lucia™ISGIRFsthpl-isg
THP1-Dual™NF-κB & IRFs● / thpd-nfis
THP1-Dual™ KO-IRF1NF-κB & IRFs, knockout of human IRF1● / thpd-koirf1
THP1-Dual™ KO IRF3NF-κB & IRFs, knockout of human IRF3● / thpd-koirf3
THP1-Dual™ KO IRF5NF-κB & IRFs, knockout of human IRF5● / thpd-koirf5
THP1-Dual™ KO IRF7NF-κB & IRFs, knockout of human IRF7● / thpd-koirf7
Transcription factor reporter cells (Mouse)
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
B16 (mouse) B16-Blue™ ISGIRFsbb-ifnabg
J774 (mouse) J774-Dual™NF-κB & IRFs● / j774d-nfis
RAW (mouse) RAW-Blue™NF-κB / AP-1raw-sp
RAW-Dual™IRFs & MIP-2 (NF-κB)● / rawd-ismip
RAW-Lucia™ ISG IRFsrawl-isg
RAW-Lucia™ ISG-KO-IRF1IRFs, knockout of mouse IRF1rawl-koirf1
RAW-Lucia™ ISG-KO-IRF3IRFs, knockout of mouse IRF3rawl-koirf3
RAW-Lucia™ ISG-KO-IRF5IRFs, knockout of mouse IRF5rawl-koirf5
RAW-Lucia™ ISG-KO-IRF7IRFs, knockout of mouse IRF7rawl-koirf7
Key signaling KO reporter cells (Human & Mouse)
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
THP-1 (human)THP1-Dual™ KO-IFNAR2NF-κB & IRFs, knockout of human IFNAR2● / thpd-koifnar2
THP1-Dual™ KO-IKKɛNF-κB & IRFs, knockout of human IKKɛ● / thpd-koikke
THP1-Dual™ KO-MyDNF-κB & IRFs, knockout of human MyD88● / thpd-komyd
THP1-Dual™ KO-TBK1NF-κB & IRFs, knockout of human TBK1● / thpd-kotbk
THP1-Dual™ KO-TREX1NF-κB & IRFs, knockout of human TREX1● / thpd-kotrex
THP1-Dual™ KO-TRIFNF-κB & IRFs, knockout of human TRIF● / thpd-kotrif
RAW (mouse) RAW-Lucia™ ISG-KO-TBK1IRFs, knockout of mouse TBK1rawl-kotbk
RAW-Lucia™ ISG-KO-TREX1IRFs, knockout of mouse TREX1rawl-kotrex
RAW-Lucia™ ISG-KO-TRIFIRFs, knockout of mouse TRIFrawl-kotrif


※ AUTOPHAGY reporter cells
  : Fluorescence (RFP::GFP)
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
HeLa (human)HeLa-Difluo™ hLC3Human LC3::GFP::RFP fusion protein heldf-hlc3
RAW (mouse)RAW-Difluo™ mLC3Mouse LC3::GFP::RFP fusion protein  rawdf-mlc3
THP-1 (human)THP1-Difluo™ hLC3Human LC3::GFP::RFP fusion protein thpdf-hlc3


※ CYTOKINE reporter cells & CHEMOKINE test cells

Interferon reporter cells
● : Colorimetric (620-655 nm) /  : Luminescent /   : Fluorescence (GFP)
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
B16 (mouse)B16-Blue™ IFN-α/βMouse type I IFNs (JAK/ISGF3 pathway)bb-ifnt1
B16-Blue™ IFN-γMouse type II IFN (JAK/STAT-1 pathway)bb-ifng
HEK293 (human)HEK-Blue™ IFN-α/βHuman type I IFNs (JAK/ISGF3 pathway)hkb-ifnab
HEK-Blue™ IFN-γHuman type II IFN (JAK/STAT-1 pathway)hkb-ifng
HEK-Blue™ IFN-λHuman type III IFN (JAK/ISGF3 pathway)hkb-ifnl
HEK-Dual™ IFN-γHuman type II IFN (JAK/STAT-1 pathway)● / hkd-ifng
Interleukin reporter cells
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
HEK293 (human)HEK-Blue™ IL-1βHuman & mouse IL-1β (NF-κB / AP-1 pathwayhkb-il1b
HEK-Blue™ IL-1RHuman & mouse IL-1α/β (NF-κB / AP-1 pathway)hkb-il1r
HEK-Blue™ IL-2Human & mouse IL-2 (STAT-5 pathway)hkb-il2
HEK-Blue™ IL-4/IL-13Human IL-4 and human & mouse IL-13 (STAT-6 pathway)hkb-il413
HEK-Blue™ IL-6Human IL-6 (STAT-3 pathway)hkb-hil6
HEK-Blue™ IL-10Human IL-10 (STAT-3 pathway)hkb-hil10
HEK-Blue™ IL-12Human & mouse IL-12 (STAT-4 pathway)hkb-il12
HEK-Blue™ IL-17Human IL-17A/F and human & mouse IL-17E (NF-κB / AP-1 pathway)hkb-il17
HEK-Blue™ IL-17CHuman & mouse IL-17C/E and human IL-17A (NF-κB / AP-1 pathway)hkb-il17c
HEK-Blue™ IL-18Human & mouse IL-18 (NF-κB / AP-1 pathway)hkb-hmil18
HEK-Blue™ IL-22Human & mouse IL-22 (STAT-3 pathway)hkb-hmil22
HEK-Blue™ IL-23Human & mouse IL-23 (STAT-3 pathway) hkb-hmil23
HEK-Blue™ IL-33Human IL-33 reporter cells (NF-κB / AP-1 pathway)hkb-hil33
Tumor necrosis factor family cytokines & Tumor growth factor reporter cells
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
HEK293 (human)HEK-Blue™ CD40LHuman CD40L (NF-κB pathway) hkb-cd40
HEK-Blue™ RANKLHuman & mouse RANKL (NF-κB / AP-1 pathway)hkb-rankl
HEK-Blue™ TNF-αHuman & mouse TNF-α (NF-κB / AP-1 pathway), knockdown of human MyD88hkb-tnfdmyd
HEK-Dual™ TNF-αHuman & mouse TNF-α (NF-κB / AP-1 pathway), knockdown of human MyD88● / hkd-tnfa
HEK-Blue™ TGF-βHuman TGF-β (TGFBRI/Smad3/4 pathway)hkb-tgfb
HEK-Blue™ TPOHuman & mouse TPO (STAT5 pathway)hkb-tpo
Chemokine test cells
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
THP-1 (human)THP1-Blue™ KI-IP10Lucia knocked into human IP10 (CXCL10) (parental cell line THP1-Blue™ NF-κB)● / 
thpb-ip10kilc


※ INFLAMMASOME test and reporter cells

Inflammasome test & reporter cells
● : Colorimetric (620-655 nm) /  : Luminescent /   : Fluorescence (GFP)
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
THP-1 (human)THP1-ASC-GFPHuman ASC::GFP fusion protein, ASC speck immunofluorescence studythp-ascgfp
THP1-KO-ASCKnockout of human ASCNonethp-koasc
THP1- KD ASCKnock-down of human ASNonethp-dasc
THP1-defCASPKnockdown of human Caspase-1Nonethp-dcasp1
THP1-KO-CASP4Knockout of human Caspase-4Nonethp-kocasp4
THP1-NLRC4Overexpression of human NLRC4Nonethp-nlrc4
THP1-KO-NLRC4Knock-out of human NLRCNonethp-konlrc4z
THP1-KO-NLRP3Knockout of human NLRP3Nonethp-konlp3
THP1-KD NLRP3Knock-down of human NLRP3Nonethp-dnlp
THP1-HMGB1-Lucia™Human HMGB1::Lucia fusion protein, pyroptosis studythp-gb1lc
THP1-KO-GSDMDKnock-out of human Gasdermin DNonethp-kogsdmdz
THP1-NullPositive control, high levels of human ASC, NLRP3 and pro-caspase-1Nonethp-null
THP1-Null2Positive Control for the KO cells in Inflammasome StudiesNonethp-nullz
RAW (mouse) RAW-ASCOverexpression of murine ASC, positive controlNoneraw-asc
RAW-ASC KO-GSDMDOverexpression of murine ASC, knockout of murine GSDMDNoneraw-kogsdmd
RAW-ASC KO-CASP11 Cellsknockout of murine Caspase-11Noneraw-kocasp11
RAW-ASC KO-NLRC4 Cellsknockout of murine NLRC4Noneraw-konlrc4
Assessing inflammasome activation
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
HEK293 (human)HEK-Blue™ IL-1βHuman and mouse IL-1βhkb-il1bv2
HEK-Blue™ IL-1RHuman and mouse IL-1 α/βhkb-il1r
HEK-Blue™ IL-18Human and mouse IL-18hkb-hmil18
THP-1 (human)THP1-HMGB1 LuciaHMGB1::Lucia reporter cellsthp-gb1lc
THP1-ASC-GFPASC::GFP reporter cellsthp-ascgfp


※ COVID-19-related cell line

COVID-19-related cell line
● : Colorimetric (620-655 nm) /  : Luminescent
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
HEK293 (human)HEK-Blue™ hACE2Human ACE2-expressing reporter Cellshkb-hace2
HEK-Blue™ hACE2-TMPRSS2Human ACE2-TMPRSS2 expressing reporter Cellshkb-hace2tpsa
293-SARS2-S-dfurSARS-CoV-2 spike (D614) with an inactive furin (dfur) cleavage siteNone293-cov2-sdf
293-SARS2-SSARS-CoV-2 spike (D614)-expressing HEK293 cellsNone293-cov2-s
293-hMyD88HEK293-derived "donor" cell line for cell fusionNone293-hmyd
A549 (human) A549-hACE2Human ACE2 Expressing CellsNonea549-hace2
A549-hACE2-TMPRSS2Human ACE2 and TMPRSS2 Expressing CellNonea549-hace2tpsa
A549-Dual™ hACE2-TMPRSS2Human ACE2 & TMPRSS2 Expressing (NF-κB-SEAP & IRF-Lucia)● / a549d-cov2r
A549-Dual™ KO-MDA5 hACE2-TMPRSS2Human MDA5 Knockout — ACE2 & TMPRSS2 Expressing● / a549d-komda5-cov2r
A549-Dual™ KO-RIG-I hACE2-TMPRSS2 Human RIG-I Knockout — ACE2 & TMPRSS2 Expressing● / a549d-korigi-cov2r
Inflammasome test & reporter cells
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
HEK293 (human)HEK-Blue™ ISGInterferon Regulatory Factor (IRF)-Inducible cellshkb-isg-1
HEK-Blue™ IL-6Human IL-6 Reporter Cellshkb-hil6
HEK-Blue™ IL-1β CellsHuman and murine interleukin-1β reporter cellshkb-il1bv2
HEK-Blue™ TNFα CellHuman TNF-α Reporter Cellshkb-tnfdmyd


※ Anti-PD-1/PD-L1 Cell-based Assay
: Luminescent
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
Raji, JurkatPD-1/PD-L1 BioIC™ (kit)Jurkat-Lucia™ TCR-hPD-1 + Raji-APC-hPD-L1 Cellsrajkt-hpd1
Raji (human)Raji-APC-Null CellControl APC for PD-1/PD-L1 BioICNoneraji-apc-null


※ ADCC and ADCP reporter T cell line
: Luminescent
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
Jurkat (human)Jurkat-Lucia™ NFAT-CD16NFAT, human CD16A (FcγRIIIA, V158 allotype) transfectedjktl-nfat-cd16
Jurkat-Lucia™ NFAT-CD32NFAT, human CD32A(FcgRIIA; H131 allotype) transfectedjktl-nfat-cd32
* Jurkat-Lucia™ NFAT-CD16 & CD32는 ADCC 및 ADCP 분석을 위한 effector cell입니다. InvivoGen의 Raji-derived Target cell과 함께 사용하실 수 있습니다 (아래 참조).


※ IMMUNE CHECKPOINT (IC) - expressing cell lines
CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONDETECTIONCAT. CODE
Raji (human)Raji-NullHuman lymphoblast CD19/CD20/Control Target CellsNoneraji-null
Raji-h4-1BBHuman lymphoblast h4-1BB expressing CellsNoneraji-h41bb
Raji-hCTLA4Human lymphoblast hCTLA4 expressing Cells Noneraji-hctla4
Raji-HER2Human lymphoblast HER2 expressing CellsNoneraji-her2
Raji-hEGFRHuman lymphoblast hEGFR expressing CellNoneraji-hegfr
Raji-hICOSHuman lymphoblast hICOS expressing CellsNoneraji-hicos
Raji-hLAG3Human lymphoblast hLAG3 expressing Cells Noneraji-hlag3
Raji-hOX40Human lymphoblast hOX40 expressing CellsNoneraji-hox40
Raji-hPD-1Human lymphoblast hPD-1 expressing CellsNoneraji-hpd1
Raji-hPD-L1Human lymphoblast hPD-L1 expressing CellsNoneraji-hpdl1
Raji-hTIGITHuman lymphoblast hTIGIT expressing CellsNoneraji-htigit
Raji-hVISTAHuman lymphoblast hVISTA expressing CellsNoneraji-hvista


제품 정보 자세히 보기

* 학술문의  T. 031-728-3236  E. technical@dawinbio.com

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