Histone methylation
Epigenetics에서 가장 대표적인 분야인 Histone methylation 관련 연구를 위한 Abcam의 다양한 제품을 만나보세요!
Histone methyltransferase activity assay
| Histone modification | Cat no. | Product name |
| Histone H3 (K4) | ab113452 | Histone H3 (K4) Methyltransferase Activity Quantification Assay Kit
|
| Histone H3 (K9) | ab113453 | Histone H3 (K9) Methyltransferase Activity Quantification Assay Kit
|
| Histone H3 (K27) | ab113454 | Histone H3 (K27) Methyltransferase Activity Quantification Assay Kit
|
Histone demethylase activity assay
| Taraget | Cat no. | Product name |
| H3K4 demethylation | ab113455 | Histone Demethylase (H3K4) Activity Quantification Assay Kit
|
H3K4me2/me3
(KDM1/LSD1) | ab113459 | KDM1/LSD1 Activity Quantification Assay Kit (Colorimetric)
|
| ab113460 | KDM1/LSD1 Activity Quantification Assay Kit (Fluorometric)
|
H3K4me2/me3
(KDM5/JARID) | ab113463 | KDM5/JARID Activity Quantification Assay Kit (Colorimetric)
|
| ab113464 | KDM5/JARID Activity Quantification Assay Kit (Fluorometric)
|
H3K9me3
(KDM4A/JHDM3A/JMJD2A, KDM4B/JMJD2B, KDM4C/GASC1/JMJD2C, KDM4D/JMJD2D)
| ab113461 | KDM4/JMJD2 Activity Quantification Assay Kit (Colorimetric)
|
| ab113462 | KDM4/JMJD2 Activity Quantification Assay Kit (Fluorometric)
|
H3K27me3
(KDM6A/UTX, KDM6B/JMJD3) | ab156910 | KDM6A/ KDM6B Activity Quantification Assay Kit (Colorimetric)
|
| ab156911 | KDM6A/KDM6B Activity Quantification Assay Kit (Fluorometric)
|
Histone demethylase inhibitor assay
| Target | Cat no. | Product name |
| H3K4me2/me3 (KDM1/LSD1) | ab113456 | Histone Demethylase KDM1/LSD1 Inhibitor Assay Kit
|
Histone methyltransferase inhibitor
| Target | Cat no. | Inhibitor | Notes |
EZH2
(H3K27me3) | ab269816 | GSK126 | Potent and selective inhibitor |
| ab269819 | GSK503 |
| ab218610 | GSK343 |
| ab269817 | EI1 |
| ab269818 | CPI-169 |
| ab146152 | UNC1999 |
| ab142215 | 3-deazaneplanocin A
| Also inhibit trimethylation of H4K20 in vitro |
| ab145628 | 3-deazaneplanocin A hydrochloride (DZNep)
|
KMT1A/SUV39
(H3K9me3) | ab144534 | Chaetocin | Also inhibit other K9-specific HMTs
|
| SET domain-containing HMTs | ab144518 | Sinefungin | Analogue of S-adenosyl-methionine (SAM)
|
EHMT1/GLP, EHMT2/G9A
(H3K9me2/3) | ab142157 | UNC0638 | Also selective against SET7/9 (H3K4 HMTase), SET8 (H4K20 HMTase), PRMT3, and SUV39H2 |
EHMT2/G9a
(H3K9me2/3) | ab141407 | BIX-01294 | Selective inhibitor |
SETD7
(H3K4me2) | ab223601 | PFI-2 | Potent and selective inhibitor |
DOT1L
(H3K79) | ab145525 | Compound 55 |
|
Histone demethylase inhibitor
| Target | Cat no. | Inhibitor | Notes |
KDM6A/UTX, KDM6B/JMJD3
(H3K27me3) | ab144396 | GSK-J1 | Also inhibit KDM5B and KDM5C |
| ab144398 | GSK-J2 | GSK-J1 isomer for use as a less-active control |
| ab144395 | GSK-J4 | Ester pro-drug of GSK-J1
|
| ab144397 | GSK-J5 | Ester pro-drug of GSK-J2
|
KDM2/7 subfamily
(H3K9me3) | ab144621 | Daminozide | Highly selective over other subfamily members (KDM3/4/5/6) and other 2-oxoglutarate oxygenase |
| JMJC-domain containing enzyme | ab144394 | IOX1 | Inhibits most 2-oxoglutarate oxygenase |
| ab144566 | Methylstat |
|
| LSD1 | ab254459 | SP-2509 | Potent, selective and reversible inhibitor |
제품 문의 Tel. 031-728-3234, 3237 E-mail. technical@dawinbio.com 카카오톡 플러스친구 ID: abcam
Histone methylation
Epigenetics에서 가장 대표적인 분야인 Histone methylation 관련 연구를 위한 Abcam의 다양한 제품을 만나보세요!
Histone methyltransferase activity assay
Histone demethylase activity assay
(KDM1/LSD1)
(KDM5/JARID)
(KDM4A/JHDM3A/JMJD2A, KDM4B/JMJD2B, KDM4C/GASC1/JMJD2C, KDM4D/JMJD2D)
(KDM6A/UTX, KDM6B/JMJD3)
Histone demethylase inhibitor assay
Histone methyltransferase inhibitor
(H3K27me3)
(H3K9me3)
(H3K9me2/3)
(H3K9me2/3)
(H3K4me2)
(H3K79)
Histone demethylase inhibitor
(H3K27me3)
(H3K9me3)
제품 문의 Tel. 031-728-3234, 3237 E-mail. technical@dawinbio.com 카카오톡 플러스친구 ID: abcam