Reporter Cell Lines표적 치료제 연구를 위한 Cytokine reporter cells & Recombinant cytokine

2022-07-18
조회수 2551

InvivoGen은 Cytokine 연구에 활용할 수 있는 Cytokine Reporter Cell Line 및 
Biological activity가 검증된 Recombinant Cytokine을 제공합니다.

◎ Cytokine Reporter Cell Line_Cytokine에 의해 유도되는 세포 내 신호 전달 경로를 모니터링 할 수  있는 tool입니다. 

  • Drug screening에 적합
  • Cytokine 정량 및 activity 확인
  • 세포 배양 과정에서 cytotoxicity 동시 확인
  • 발색 / 발광 반응으로 결과 확인

Interleukin reporter cells

CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONCAT. CODE
HEK293 (human)HEK-Blue™ IL-1βHuman & Mouse IL-1β (NF-κB / AP-1 pathway)hkb-il1bv2
HEK-Blue™ IL-1RHuman & Mouse IL-1α/β (NF-κB / AP-1 pathway)hkb-il1r
HEK-Blue™ IL-2Human & Mouse IL-2 and  IL-15 (STAT-5 pathway)hkb-il2
HEK-Blue™ CD122/CD132Human IL-2 and IL-15 (STAT-5 pathway)hkb-il2bg
HEK-Blue™ IL-4/IL-13Human IL-4 and Human & Mouse IL-13 (STAT-6 pathway)hkb-il413
HEK-Blue™ IL-5Human & Mouse IL-5 (STAT-5 pathway)hkb-il5
HEK-Blue™ IL-6Human IL-6 (STAT-3 pathway)hkb-hil6
HEK-Blue™ IL-7Human & Mouse IL-7 (STAT-5 pathway)hkb-il7
HEK-Blue™ IL-9Human & Mouse IL-9 (STAT-5 pathway)hkb-il9
HEK-Blue™ IL-10Human & Mouse IL-10 (STAT-3 pathway)hkb-il10
HEK-Blue™ IL-11Human & Mouse IL-11 (STAT-3 pathway)hkb-hil11r
HEK-Blue™ IL-12Human & Mouse IL-12 (STAT-4 pathway)hkb-il12
HEK-Blue™ IL-17Human IL-17A/F and Human & Mouse IL-17E (NF-κB / AP-1 pathway)hkb-il17
HEK-Blue™ IL-17CHuman & Mouse IL-17C/E and Human IL-17A (NF-κB / AP-1 pathway)hkb-il17c
HEK-Blue™ IL-18Human & Mouse IL-18 (NF-κB / AP-1 pathway)hkb-hmil18
HEK-Blue™ IL-22Human & Mouse IL-22 (STAT-3 pathway)hkb-il22
HEK-Blue™ IL-23Human & Mouse IL-23 (STAT-3 pathway) hkb-il23
HEK-Blue™ IL-33Human IL-33 (NF-κB / AP-1 pathway)hkb-hil33
HEK-Blue™ IL-36Human IL-36 (NF-κB / AP-1 pathway)hkb-hil36r

Interferon reporter cells

CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONCAT. CODE
HEK293 (human)HEK-Blue™ IFN-α/β Human type I IFNs (JAK/STAT/ISGF3 pathway)hkb-ifnab
HEK-Blue™ IFN-γHuman type II IFN (JAK/STAT-1 pathway)hkb-ifng
HEK-Dual™ IFN-γHuman type II IFN (JAK/STAT-1 pathway)hkd-ifng
HEK-Blue™ IFN-λHuman type III IFNs (JAK/STAT/ISGF3 pathway)hkb-ifnl
HEK-Blue™ ISGInterferon Regulatory Factor (IRF)-Inducible cells (STING/TBK1/IRF3 pathway)hkb-isg-1
B16 (mouse)B16-Blue™ IFN-α/βMouse type I IFNs (JAK/STAT/ISGF3 pathway)bb-ifnt1
B16-Blue™ IFN-γMouse type II IFN (JAK/STAT/ISRE pathway)bb-ifng
RAW 264.7 (mouse) RAW-Lucia™ ISG Interferon Regulatory Factor (IRF)-Inducible cells (STING/TBK1/IRF3 pathway)rawl-isg

Growth Factor Reporter Cells

CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONCAT. CODE
HEK293 (human)HEK-Blue™ GM-CSFHuman GM-CSF (JAK2/STAT5 pathway)hkb-hgmcsfr
HEK-Blue™ TGF-βHuman & Mouse TGFβ (TGF-β/Smad pathway)hkb-tgfbv2
HEK-Blue™ TPOHuman & Mouse TPO (JAK2/STAT5 pathway)hkb-tpo

Tumor Necrosis Factor Reporter Cells

CELL LINEPRODUCTPATHWAYS STUDIED / DESCRIPTIONCAT. CODE
HEK293 (human)HEK-Blue™ CD40LHuman CD40L (NF-κB pathway)hkb-cd40
HEK-Blue™ TNF-αHuman & Mouse TNF-α (NF-κB/AP-1 pathway), knockout of human MyD88hkb-tnfdmyd
HEK-Dual™ TNF-αHuman TNF-α (NF-κB/AP-1 pathway), knockout of human MyD88hkd-tnfa
HEK-Blue™ RANKL Human & Mouse RANKL (NF-κB/AP-1 pathway)hkb-rankl


◎ Recombinant Cytokine_InvivoGen은 recombinant DNA 기술로 생산된 다양한 Cytokine을 제공합니다.  

  • High purity
  • Endotoxin test 완료
  • Biological activity 검증 완료
PRODUCTSIZECAT. CODEAPPLICATIONSOURCE
Recombinant human CD40L10 µgrcyec-hcd40lCell culture applicationsE. coli
Recombinant human IFN-α2b1 µgrcyc-hifna2bCellular assays, ELISACHO cells
Recombinant human IFN-γ20 µgrcyec-hifngCell culture applicationsE. coli
Recombinant human IL-1β10 µgrcyec-hil1bCell culture applicationsE. coli
Recombinant human IL-410 µgrcyec-hil4Cell culture applicationsE. coli
Recombinant human IL-610 µgrcyec-hil6Cell culture applicationsE. coli
Recombinant human IL-1210 µgrcyc-hil12Cell culture applicationsCHO cells
Recombinant mouse IL-1210 µgrcyc-mil12Cell culture applicationsCHO cells
Recombinant human IL-1810 µgrcyec-hil18Cell culture applicationsE. coli
Recombinant human TGF-β110 µgrcyc-htgfb1Cell culture applicationsHEK293 cells
Recombinant human TNF-α20 µgrcyc-htnfaCell culture applicationsCHO cells


[학술문의] T. 031-728-3236 E. technical@dawinbio.com

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