InvivoGen은 Cytokine 연구에 활용할 수 있는 Cytokine Reporter Cell Line 및
Biological activity가 검증된 Recombinant Cytokine을 제공합니다.
◎ Cytokine Reporter Cell Line_Cytokine에 의해 유도되는 세포 내 신호 전달 경로를 모니터링 할 수 있는 tool입니다.
- Drug screening에 적합
- Cytokine 정량 및 activity 확인
| - 세포 배양 과정에서 cytotoxicity 동시 확인
- 발색 / 발광 반응으로 결과 확인
|
Interleukin reporter cells
| CELL LINE | PRODUCT | PATHWAYS STUDIED / DESCRIPTION | CAT. CODE |
| HEK293 (human) | HEK-Blue™ IL-1β | Human & Mouse IL-1β (NF-κB / AP-1 pathway) | hkb-il1bv2 |
| HEK-Blue™ IL-1R | Human & Mouse IL-1α/β (NF-κB / AP-1 pathway) | hkb-il1r |
| HEK-Blue™ IL-2 | Human & Mouse IL-2 and IL-15 (STAT-5 pathway) | hkb-il2 |
| HEK-Blue™ CD122/CD132 | Human IL-2 and IL-15 (STAT-5 pathway) | hkb-il2bg |
| HEK-Blue™ IL-4/IL-13 | Human IL-4 and Human & Mouse IL-13 (STAT-6 pathway) | hkb-il413 |
| HEK-Blue™ IL-5 | Human & Mouse IL-5 (STAT-5 pathway) | hkb-il5 |
| HEK-Blue™ IL-6 | Human IL-6 (STAT-3 pathway) | hkb-hil6 |
| HEK-Blue™ IL-7 | Human & Mouse IL-7 (STAT-5 pathway) | hkb-il7 |
| HEK-Blue™ IL-9 | Human & Mouse IL-9 (STAT-5 pathway) | hkb-il9 |
| HEK-Blue™ IL-10 | Human & Mouse IL-10 (STAT-3 pathway) | hkb-il10 |
| HEK-Blue™ IL-11 | Human & Mouse IL-11 (STAT-3 pathway) | hkb-hil11r |
| HEK-Blue™ IL-12 | Human & Mouse IL-12 (STAT-4 pathway) | hkb-il12 |
| HEK-Blue™ IL-17 | Human IL-17A/F and Human & Mouse IL-17E (NF-κB / AP-1 pathway) | hkb-il17 |
| HEK-Blue™ IL-17C | Human & Mouse IL-17C/E and Human IL-17A (NF-κB / AP-1 pathway) | hkb-il17c |
| HEK-Blue™ IL-18 | Human & Mouse IL-18 (NF-κB / AP-1 pathway) | hkb-hmil18 |
| HEK-Blue™ IL-22 | Human & Mouse IL-22 (STAT-3 pathway) | hkb-il22 |
| HEK-Blue™ IL-23 | Human & Mouse IL-23 (STAT-3 pathway) | hkb-il23 |
| HEK-Blue™ IL-33 | Human IL-33 (NF-κB / AP-1 pathway) | hkb-hil33 |
| HEK-Blue™ IL-36 | Human IL-36 (NF-κB / AP-1 pathway) | hkb-hil36r |
Interferon reporter cells
| CELL LINE | PRODUCT | PATHWAYS STUDIED / DESCRIPTION | CAT. CODE |
| HEK293 (human) | HEK-Blue™ IFN-α/β | Human type I IFNs (JAK/STAT/ISGF3 pathway) | hkb-ifnab |
| HEK-Blue™ IFN-γ | Human type II IFN (JAK/STAT-1 pathway) | hkb-ifng |
| HEK-Dual™ IFN-γ | Human type II IFN (JAK/STAT-1 pathway) | hkd-ifng |
| HEK-Blue™ IFN-λ | Human type III IFNs (JAK/STAT/ISGF3 pathway) | hkb-ifnl |
| HEK-Blue™ ISG | Interferon Regulatory Factor (IRF)-Inducible cells (STING/TBK1/IRF3 pathway) | hkb-isg-1 |
| B16 (mouse) | B16-Blue™ IFN-α/β | Mouse type I IFNs (JAK/STAT/ISGF3 pathway) | bb-ifnt1 |
| B16-Blue™ IFN-γ | Mouse type II IFN (JAK/STAT/ISRE pathway) | bb-ifng |
| RAW 264.7 (mouse) | RAW-Lucia™ ISG | Interferon Regulatory Factor (IRF)-Inducible cells (STING/TBK1/IRF3 pathway) | rawl-isg |
Growth Factor Reporter Cells
| CELL LINE | PRODUCT | PATHWAYS STUDIED / DESCRIPTION | CAT. CODE |
| HEK293 (human) | HEK-Blue™ GM-CSF | Human GM-CSF (JAK2/STAT5 pathway) | hkb-hgmcsfr |
| HEK-Blue™ TGF-β | Human & Mouse TGFβ (TGF-β/Smad pathway) | hkb-tgfbv2 |
| HEK-Blue™ TPO | Human & Mouse TPO (JAK2/STAT5 pathway) | hkb-tpo |
Tumor Necrosis Factor Reporter Cells
| CELL LINE | PRODUCT | PATHWAYS STUDIED / DESCRIPTION | CAT. CODE |
| HEK293 (human) | HEK-Blue™ CD40L | Human CD40L (NF-κB pathway) | hkb-cd40 |
| HEK-Blue™ TNF-α | Human & Mouse TNF-α (NF-κB/AP-1 pathway), knockout of human MyD88 | hkb-tnfdmyd |
| HEK-Dual™ TNF-α | Human TNF-α (NF-κB/AP-1 pathway), knockout of human MyD88 | hkd-tnfa |
| HEK-Blue™ RANKL | Human & Mouse RANKL (NF-κB/AP-1 pathway) | hkb-rankl |
◎ Recombinant Cytokine_InvivoGen은 recombinant DNA 기술로 생산된 다양한 Cytokine을 제공합니다.
| | - Biological activity 검증 완료
|
| PRODUCT | SIZE | CAT. CODE | APPLICATION | SOURCE |
| Recombinant human CD40L | 10 µg | rcyec-hcd40l | Cell culture applications | E. coli |
| Recombinant human IFN-α2b | 1 µg | rcyc-hifna2b | Cellular assays, ELISA | CHO cells |
| Recombinant human IFN-γ | 20 µg | rcyec-hifng | Cell culture applications | E. coli |
| Recombinant human IL-1β | 10 µg | rcyec-hil1b | Cell culture applications | E. coli |
| Recombinant human IL-4 | 10 µg | rcyec-hil4 | Cell culture applications | E. coli |
| Recombinant human IL-6 | 10 µg | rcyec-hil6 | Cell culture applications | E. coli |
| Recombinant human IL-12 | 10 µg | rcyc-hil12 | Cell culture applications | CHO cells |
| Recombinant mouse IL-12 | 10 µg | rcyc-mil12 | Cell culture applications | CHO cells |
| Recombinant human IL-18 | 10 µg | rcyec-hil18 | Cell culture applications | E. coli |
| Recombinant human TGF-β1 | 10 µg | rcyc-htgfb1 | Cell culture applications | HEK293 cells |
| Recombinant human TNF-α | 20 µg | rcyc-htnfa | Cell culture applications | CHO cells |
[학술문의] T. 031-728-3236 E. technical@dawinbio.com
InvivoGen은 Cytokine 연구에 활용할 수 있는 Cytokine Reporter Cell Line 및
Biological activity가 검증된 Recombinant Cytokine을 제공합니다.
◎ Cytokine Reporter Cell Line_Cytokine에 의해 유도되는 세포 내 신호 전달 경로를 모니터링 할 수 있는 tool입니다.
Interleukin reporter cells
Interferon reporter cells
Growth Factor Reporter Cells
Tumor Necrosis Factor Reporter Cells
◎ Recombinant Cytokine_InvivoGen은 recombinant DNA 기술로 생산된 다양한 Cytokine을 제공합니다.
[학술문의] T. 031-728-3236 E. technical@dawinbio.com