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ToolsApoptosis 연구를 하시나요? abcam 에서 제공하는 다양한 Solution 을 확인하세요!

Abcam
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Apoptosis : Tools for cell death


  Apoptosis 를 확인하기 위한 Experimental Tools


- Annexin V Apoptosis Kits

  : Annexin V 가 세포 표면에 전시된 Phosphatidylserin (PS) 를 검출함으로써 Apoptosis 확인

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         Negative control-AG6173 untreated cells                 Positive control- AG6173 cells irradiated at 10Gy


Cat no. Product name Annexin-V conjugatescounterstainSize 
ab14085Annexin V-FITC Apoptosis Staining / Detection KitFITCPI100 tests
ab273274Annexin V-PE Apoptosis Staining / Detection Kit
(with dead cell stain)
PESYTOX25 tests
ab14153Annexin V-EGFP Apoptosis Staining / Detection KitEGFPPI100 tests
ab14143Annexin V/ANXA5-Cy3 Apoptosis Staining / Detection Reagent
Cy3-100 tests
ab14144Annexin V-Cy3 Apoptosis Staining / Detection Kit with SYTOXCy3SYTOX100 tests
ab14150Annexin V-Cy5 Apoptosis Staining / Detection KitCy5-100 tests
ab14083Propidium Iodide

1 ml


- TUNEL assay kit

: DNA fragmentation 의 말단 부분에 Terminal deoxynucleotidyl Transferase (TdT) enzyme 을 결합시켜 형광 또는 발색 반응으로 Apoptosis 확인


Cat no. Product name DetectionSize 
ab66108In situ Direct DNA Fragmentation (TUNEL) Assay Kit형광, 495/519nm50 tests
ab66110In situ BrdU-Red DNA Fragmentation (TUNEL) Assay Kit형광, 488/576nm60 assays
ab206386In situ Apoptosis Detection Kit발색30 or 60 slides


- Apotrack™ Human Cytochrome C Apoptosis Cocktail & Kit

: Cytochrome C 를 포함한 Apoptosis 에 관여하는 단백질들이 미토콘드리아 내벽에서 세포질로 이동하는 것을 확인하는 제품으로 WB 와 ICC (세포 형광 염색) 방식 중 선택 가능


1. ab110415, WB Antibody Cocktail

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   2. ab110417, ICC Antibody Kit

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Cat no. Product name ReactivityTarget list
ab110417Cytochrome c Apoptosis ICC Antibody Kit
Mouse, Rat, HumanComplex V alpha, Cytochrome c
ab110415ApoTrack™ Cytochrome c Apoptosis WB Antibody CocktailHumanComplex V alpha, Cytochrome c,
PDH-E1-alpha, GAPDH


- Human Apoptosis Membrane Antibody Array, ab134001 

: Apoptosis 에 관여하는 43 가지의 단백질 발현 양을 한 번에 상대 정량 가능 

  Sandwich ELISA 방식의 실험 과정과 WB 의 detection 원리를 이용하여 결과 확인


Cat no. Product name ReactivitySize
ab134001Human Apoptosis Antibody Array - Membrane (43 Targets)Human2 membranes
4 membranes
8 membranes
Target ListBad, Bax, Bcl-2, Bcl-w, BID, BIM, Caspase3, caspase8, CD40, CD40L, cIAP-2, cytoC, DR6, Fas, FasL, HSP27, HSP60, HSP70, HTRA, IGF-I, IGF-II, IGFBP-1, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, IGFBP-6, IGF-1sR, livin, p21, p27, p53, SMAC, Survivin, sTNF-R1, sTNF-R2, TNF-alpha, TNF-beta, TRAILR-1, TRAILR-2, TRAILR-3, TRAILR-4, XIAP


- Popular Apoptosis inducers 와 inhibitors

: Apoptosis 를 유도 또는 억제하는 biochemical 리스트


Apoptosis inducers

 Cat no. Product name제품 설명
ab141227Apoptosis Activator 2 (AAII)Cytochrome C, caspase activator and apoptosis inducer
ab120093CycloheximideProtein synthesis inhibitor
ab120797Mitomycin C (MMC)Anticancer and antibiotic agent
ab141054OxaliplatinPlatinum anticancer agent. Induces DNA cross-linking.
ab141107CPT 11 (Irinotecan)Potent DNA topoisomerase I inhibitor
ab120115CamptothecinDNA topoisomerase inhibitor
ab120081FCCPMitochondrial oxidative phosphorylation inhibitor


Apoptosis inhibitors

Cat no. Product name제품 설명
ab120487z-VAD-(OMe)-FMKCell permeable, irreversible general caspase inhibitor
ab120488z-D(OMe)E(OMe)VD(OMe)-FMKCell permeable caspase 3 inhibitor
ab141382z-IETD-FMKCaspase 8 inhibitor
ab120886Pifithrin-μInhibitor of p53-mediated apoptosis



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#Abcam #다윈바이오 #DAWINBIO #Apoptosis #Annexin V #TUNEL assay




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